It's not the house vent. Both sinks drain through a common elbow. So, when one sink is closed, the air in the pipe before the elbow has only the remaining sink through which to vent. The way the drain is designed, if you leave the screen in place, it has damn little space for water/air to exchange. Burping (opening the other sink to let the air pressure out) gets it working again. To me, it's a sucky design for a sink drain.